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Table 1 Results from fluorescent in situ hybridisation (FISH) in fetal testis using two chromosome 21-specific probes (red and green)

From: On the paternal origin of trisomy 21 Down syndrome

   No of signals green/red  
Case No/Id Gest. Age (wks) 2gr/2r 3gr/3r 1gr/1r 2gr/1r 1gr/2r 2gr/3r 3gr/2r Total no of scored cells
8787 18 3927 - 35* 1 6 2 - 3971
8795 17 2510 - 5 - 2 - - 2517
5A 14 3294 1# 11** 3 6 - 1 3316
6A 19 2010 - 3 1 22 - 2 2038
Total   11741 1 54 5 36 2 3 11842
  1. *One of these nuclei contained only one chromosome 18 signal and was interpreted as having either monosomy 21 together with monosomy 18 or being haploid; the remaining showing two chromosome 18 signals were recorded as either false negative monosomy 21 (due to somatic pairing) or true monosomy 21 [91, 92].
  2. **These nuclei contained two chromosome 18 signals and were also recorded as false negative monosomy 21 (due to somatic pairing) or true monosomy 21[91, 92].
  3. #This nucleus had 3 × 18 signals and was recorded as being triploid.