|
-
|
Whole DNA damage and repair
|
Genotoxicity testing or biomonitoring of genotoxic exposure and effect
|
[1–15]
|
|
Gene-specific
|
DNA damage and repair within the vicinity of the gene of interest
|
Analysis of damage and repair of genes related with cancer (TP53, KRAS, APC, p53)
|
[41, 46, 51, 53–58].
|
| | |
Analysis of damage of genes Ret, Ab1 and Trp53 as biomarker of X-radiation exposure in vivo
|
[59]
|
| | |
Spatial distribution of chromosome-specific DNA sequences
|
[40]
|
|
Chromosome locus-specific (centromere-, telomere- and region-specific)
|
DNA damage within the vicinity of the locus of interest
|
Analysis of leukaemia-specific chromosome damage
|
[61]
|
| | |
Analysis of sensitivity of telomeres toward anticancer drugs
|
[63–65]
|
|
WCP
|
DNA damage within the chromosome of interest
|
Distribution of DNA damage in genome
|
[44, 60]
|
| | |
Genetic alterations in carcinogenesis of the upper aerodigestive tract
|
[62]
|
|
Selected probes
|
Different genomic regions
|
Transcription-coupled DNA repair
|
[48]
|
| | |
Elucidation of comet formation
|
[44–46, 51, 52]
|
