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Figure 2 | Molecular Cytogenetics

Figure 2

From: Microdeletion syndromes disclose replication timing alterations of genes unrelated to the missing DNA

Figure 2

Fluorescent signals in PHA-stimulated lymphocytes at interphase, following FISH with RB1. (a) – (c) cells with two singlets (SS cells) in which neither allele has replicated; (d) – (f) cells with two doublets (DD cells) in which both alleles have replicated; and (g) – (i) cells with one singlet and one doublet (SD cells), which are S-phase cells in which one allele has replicated while its partner has not.

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