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Figure 2 | Molecular Cytogenetics

Figure 2

From: Submicroscopic deletions of 11q24-25 in individuals without Jacobsen syndrome: re-examination of the critical region by high-resolution array-CGH

Figure 2

11q24-25 rearrangements found in subjects 1 and 2. (a) Nimblegen array (385 K) profiles of chromosome 11 showed a 5.04 Mb duplication and a 6.18 Mb deletion detected in subject 1. FISH confirmation of the duplication of clone RP11-50B3 (b) and deletion of clone RP11-206H19 (AP003775.3) (c) in subject 1. (d) Nimblegen array (385 K) profiles of chromosome 11 showed a 4.74 Mb deletion of chromosome 11q24.2-24.3 in subject 2. FISH confirmation of the deletion of clones RP11-50B3 and RP11-206H19 (AP003775.3) in subject 2 is shown in (e) and (f), respectively. Arrow indicates duplicated chromosome and arrowhead the deleted chromosomes.

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Molecular Cytogenetics

ISSN: 1755-8166