Table 3 Frequencies of NCA, P/LP CNV and ROH between singleton and twin fetuses with CHDs
CMA results | Total  (n = 1118) | Isolated  (n = 887) | Nonisolated  (n = 231) | p | Singleton fetuses with CHD | Twin fetuses with CHD | p (Singleton vs. Twin) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total  (n = 961) | Isolated  (n = 778) | Nonisolated  (n = 183) | P | Total  (n = 157) | Isolated (n = 109) | Nonisolated (n = 48) | p | |||||||
CA | NCA (n, %) | 102 (9.1) | 39 (4.4) | 63 (27.3) |  < 0.001* | 80 (8.3) | 32 (4.1) | 48 (26.2) |  < 0.001* | 22 (14.0) | 7 (6.4) | 15 (31.3) |  < 0.001* | 0.022* |
CNV (n, %) | 95 (8.5) | 68 (7.7) | 27 (11.7) | 0.051* | 83 (8.6) | 60 (7.7) | 23 (12.6) | 0.035* | 12 (7.6) | 8 (7.3) | 4 (8.3) | 0.829# | 0.679* | |
Total (n, %) | 197 (17.6) | 107 (12.1) | 90 (39.0) |  < 0.001* | 163 (17.0) | 92 (11.8) | 71 (38.8) |  < 0.001* | 34 (21.7) | 15 (13.8) | 19 (39.6) |  < 0.001* | 0.152* | |
ROH (n, %) | 4 (0.4) | 2 (0.2) | 2 (0.9) | 0.191# | 4 (0.4) | 2 (0.3) | 2 (1.1) | 0.166# | 0 | 0 | 0 | – | – |  |