Table 2 Performance of NIPT in screening chromosomal aberrations in different nuchal translucency thickness groups
Group A (NT 2.5–2.9 mm) n = 864 | Group B (NT 3.0–3.4 mm) n = 350 | Group C (NT ≥ 3.5 mm) n = 256 | |
|---|---|---|---|
High-risk in NIPT | 32 (3.7%) | 29 (8.3%) | 67 (26.2%) |
Chromosome result available | 22 (68.8%) | 17 (58.6%) | 48 (71.6%) |
Chromosomal aberrations | 20 | 17 | 47 |
No aberrations detected | 2 | 0 | 1 |
Positive predictive value | 90.9% | 100% | 97.9% |