Table 1 Detection rates of abnormal karyotypes among different indications for prenatal genetic cordocentesis
Indication for genetic diagnosis | Cases (%) | Abnormal karyotype(n) | (%) |
|---|---|---|---|
Ultrasound soft markers | 2478 (73.16) | 50 | 2.02 |
USAF | 403 (11.90) | 45 | 11.17 |
Advanced maternal age | 114 (3.37) | 22 | 19.30 |
Abnormal MSS | 77 (2.27) | 6 | 7.79 |
EMFCA | 15 (0.44) | 5 | 33.33 |
NIPT positive | 66 (1.94) | 31 | 46.97 |
KCAA | 52 (1.54) | 23 | 44.23 |
Total | 3387 | 182 | 5.37 |