Table 1 Hematological characteristics in comparison with national and international studies
Variables | Present study | Pakistan 1 | Pakistan 2 | Pakistan 3 | China 6 | Korea 7 | India 8 | Turkey 9 | Greece 10 | Taiwan 11 | Singapore 12 | Spain 13 | Germany 14 | Poland 15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total No. of Patients | 177 | 45 | 46 | 71 | 508 | 176 | 40 | 54 | 855 | 189 | 43 | 640 | 216 | 863 |
Median age(years) | 51.7 | 64 | Mean 43.09 | 60 | 49 | 57 | 42 | 67 | 73.1 | 56 | Mean 64 | 66 | 73 | 70 |
Mean Hb (g/dl) | 7.8 | 7.7 | 6.52 | – | 6.3 | – | 6.84 | 9.0 | 9.5 | 8 .0 | 7.7 | – | – | 9.1 |
Mean MCV (fl) | 90 | 89.4 | 89.4 | – | – | – | – | – | – | – | – | – | – | 97 |
Mean TLC (×109/l) | 8.8 | 5.7 | 3.4 | – | 3.0 | – | 4.45 | 3.8 | 7.52 | 3.3 | 5.6 | – | – | – |
Mean Platelet (×109/l) | 82 | 83 | 60 | – | 42 | – | 85 | 163 | 158 | 61 | 101 | – | – | 129 |
MDS Category | ||||||||||||||
RCMD % | 22 | 53.3 | 52.2 | 52 | – | 37 | 10 | – | 14.3 | – | – | - | 31 | 28.3 |
RAEB-II % | 19.7 | 4.4 | 6.5 | 23.9 | 21.1 | 21 | 15 | 30 | 14.4 | 18.5 | 7 | 12 | 11 | 19.6 |
RAEB-I % | 19.2 | 4.4 | 6.5 | 11.3 | 27 | 29 | 18 | 7 | 18.9 | 40.7 | 16.3 | 32 | 8 | 13.9 |
Hypoplastic MDS % | 13 | – | – | – | – | – | – | – | – | – | – | – | – | – |
RA % | 9 | – | – | 8.5 | 43.9 | 12 | 37 | 57 | 20.6 | 32.5 | 38.1 | 29 | 9 | 19.7 |
RARS % | 7.9 | – | – | 2.8 | 2.8 | – | 7.5 | – | 6.2 | 8 | 14 | 12 | 4 | 6.7 |
RCUD % | 3.3 | 22.2 | RCUD–RA 26 | – | – | – | – | – | – | – | – | – | – | – |
RCMD-RS % | 2.8 | – | 2.2 | 1.4 | – | – | 2.5 | – | 2.8 | – | – | – | 13 | 2.1 |
MDS with 5q % | 2.20 | – | – | – | – | – | 10 | 6 | 1.9 | – | – | – | 2 | 4.6 |
RCC % | 0.5 | – | – | – | – | – | – | – | – | – | – | – | – | – |
MDS-U % | – | 15.5 | 6.5 | – | – | 1 | – | – | – | – | – | – | – | 5.1 |