| NGS | aCGH | P-value |
---|---|---|---|
Number of patients undergoing PGS | 135 | 202 | — |
Number of embryos diagnose by PGSa | 472 | 827 | — |
 Euploid | 180 (38.1%) | 364 (44.0%) | 0.04* |
 Aneuploid | 219 (46.4%) | 370 (44.7%) | 0.60 |
 Mosaic | 25 (5.3%) | 14 (1.7%) | <0.01** |
 Segmental aneuploid | 48 (10.2%) | 79 (9.6%) | 0.77 |
Number of patients with no euploid embryo to transfera | 44 (32.6%) | 42 (20.8%) | 0.02* |
 Aneuploid | 23 (17.0%) | 32 (15.8%) | 0.77 |
 Mosaic | 6 (4.4%) | 0 (0%) | — |
 Segmental aneuploid | 15 (11.1%) | 10 (5.0%) | 0.05 |
Number of transferred patientsa | 90 (66.7%) | 129 (63.9%) | — |
Mean female age (years)b | 37.5 ± 5.5 (27–53) | 37.2 ± 4.5 (27–51) | 0.68 |
Indicationsa | |||
 Severe male factor | 9 (10%) | 25 (19%) | 0.08 |
 Advanced female age (≥36 years) | 32 (36%) | 42 (33%) | |
 Repeated implantation failure | 32 (36%) | 47 (36%) | |
 Oocyte –donation cycle for SET | 17 (19%) | 15 (12%) | |
Baseline AMH (ng/mL)b | 4.5 ± 3.7 | 4.9 ± 3.6 | 0.42 |
Antral follicle countb | 11.0 ± 4.6 | 11.2 ± 4.7 | 0.82 |
Mean endometrial thickness (mm)b | 9.3 ± 1.8 | 9.2 ± 1.4 | 0.72 |
Clinical outcomes after the first cryotransfera | |||
 HCG(+) pregnancy | 66 (73%) | 78 (60%) | 0.048* |
 Implantation | 64 (53%) | 67 (45%) | 0.043* |
 Clinical pregnancy | 59 (66%) | 73 (57%) | 0.18 |
 Ongoing pregnancy | 51 (57%) | 59 (46%) | 0.11 |
 Multiple pregnancy | 3 (3%) | 4 (3%) | 1.00 |
 Miscarriage | 8 (9%) | 14 (11%) | 0.48 |
Average transferred embryo per cryotransferb | 1.2 ± 0.5 | 1.2 ± 0.4 | 0.11 |