Fig. 2

‘Normal sizes’ of heterochromatic regions within the human genome. a) Acrocentric short arms are normal size if they have a length between half of 18p and 2/3 of 17p; three different variants all considered as ‘normal’ are depicted for chromosome 14 in the center part of this figure. An example each, for a 14p- and a 14p + are shown left right of these three normal chromosome 14 variants. b) For 9q12 three normal sized variants are shown here as before for 14p in figure-part A. Normal sized is for 9p12 if it is between half size of 16p and full 16p. 9qh- and 9qh + are shown as well correspondingly smaller than half of 16p or larger than whole 16p. c) For centromeric size the reference size may be the diameter of a chromatide of the same metaphase or stained chromosome. Cen- and cen + heteromorphisms are clearly smaller or larger than a chromatide diameter, respectively