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Figure 2 | Molecular Cytogenetics

Figure 2

From: A novel insertion ins(18;5)(q21.1;q31.2q35.1) in acute myeloid leukemia associated with microdeletions at 5q31.2, 5q35.1q35.2 and 18q12.3q21.1 detected by oligobased array comparative genomic hybridization

Figure 2

mBanding analyses of chromosomes 5 and 18. The single color gallery tool in the ISIS software shows assigned false colors (FC) representing individual color schemes of labeled chromosomes arranged in its capture sequence (fluorescein isothiocyanate) FITC, (spectrum orange) SpO, (texas red) TR, (cyanine 5) Cy5, (7-diethylaminocoumarin-3-carboxylic acid, succinimidyl ester) DEAC, together with an inverted gray scale image of the DAPI image (Inv). Panel A. mBanding analysis using the XCyte 5 probe. The top panel shows a normal chromosome 5, the middle panel shows the deleted chromosome 5, and the lower panel shows the 5q-insertion on der(18)ins(18;5). To the right is a schematic representation of the localization of the different multicolor probes of XCyte 5 relative to the ideogram of chromosome 5 together with breakpoints marked by black horizontal lines. Panel B. mBanding analysis using the XCyte 18 probe. The top panel shows a normal chromosome 18 and the lower panel the der(18)ins(18;5). To the right is a schematic representation of the localization of the different multicolor probes of XCyte 18 relative to the ideogram of chromosome 18 together with the breakpoint marked by a black horizontal line.

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Molecular Cytogenetics

ISSN: 1755-8166