Table 2 List of systems/processes associated with genes in the amplified region as identified by IPA
Category | p-values | Molecules encoded from duplicated region |
|---|---|---|
Auditory and Vestibular System Development and Function | 2.20E-03 | GABRA5,GABRB3 |
Auditory Disease | 2.20E-03 - 8.41E-03 | GABRA5,GABRB3 |
Behaviour | 1.36E-03 | GABRB3 |
Cancer | 1.07E-02 - 4.42E-04 | ATP10A,MKRN3,SNRPN,UBE3A |
Cardiac Arteriopathy | 4.33E-03 | GABRA5,GABRB3,GABRG1,GABRG3 |
Cardiovascular Disease | 4.33E-03 - 4.44E-08 | GABRA5,GABRB3,GABRG1,GABRG3 |
Cell cycle | 1.02E-02 - 4.42E-04 | HERC2, UBE3A |
Cell Death and Survival | 3.03E-03 - 1.17E-03 | GABRA5,GABRB3 |
Cell Morphology | 2.68E-04 - 1.08E-02 | OCA2, GABRA5,GABRB3,NDN |
Cell-To-Cell Signalling and Interaction | 1.57E-01 - 8.12E-03 | NDN, UBE3A |
Cellular Assembly and Organization | 1.02E-02 - 7.54E-03 | SNURF |
Cellular Compromise | 3.36E-05 - 1.72E-03 | GABRA5,GABRB3 |
Cellular Development | 8.05E-03 - 3.36E-05 | NDN, UBE3A |
Cellular Growth and Proliferation | 8.05E-03 - 5.96E-04 | NDN, UBE3A |
Cellular Movement | 2.68E-04 - 1.51E-04 | GABRA5,GABRB3,NDN |
Connective Tissue Development and Function | 1.57E-01 | NDN |
Connective Tissue Disorders | 1.40E-03 - 1.40E-08 | GABRA5,GABRB3,GABRG3 |
Developmental Disorder | 1.17E-02 - 4.69E-10 | GABRB3,GABRG3,MAGEL2,MKRN3,NDN,SNRPN,UBE3A |
DNA Replication, Recombination, and Repair | 1.15E-02 | SNRPN |
Endocrine System Disorders | 8.57E-03 | MKRN3 |
Gene Expression | 1.15E-02 - 6.35E-05 | NDN,SNRPN,UBE3A |
Hair and Skin Development and Function | 4.97E-03 | OCA2 |
Hematological Disease | 5.83E-03 | UBE3A |
Hepatic System Development and Function | 1.57E-01 | NDN |
Hereditary Disorder | 1.17E-02 - 4.69E-10 | GABRA5,GABRB3,GABRG3,MAGEL2,MKRN3,NDN,SNRPN, UBE3A |
Infectious Disease | 4.68E-05 | GABRA5,GABRB3,GABRG3 |
Kidney Failure | 2.45E-01 | GABRB3 |
Liver Fibrosis | 1.57E-01 | NDN |
Nervous System Development and Function | 8.12E-03 - 1.51E-04 | GABRA5,GABRB3,NDN, UBE3A |
Neurological Disease | 1.17E-02 - 5.59E-09 | GABRA5,GABRB3,GABRG3,UBE3A |
Nutritional Disease | 1.82E-03 - 3.03E-06 | GABRA5,GABRB3,GABRG3 |
Organ Morphology | 5.87E-03 - 2.20E-03 | GABRA5,GABRB3, UBE3A |
Organismal Functions | 5.87E-03 | NDN |
Organismal Injury and Abnormalities | 2.45E-01 - 3.74E-06 | GABRA5,GABRB3,GABRG3 |
Protein Degradation | 1.33E-03 | UBE3A |
Protein Synthesis | 1.33E-03 | UBE3A |
Psychological Disorders | 5.57E-04 - 1.34E-06 | GABRA5,GABRB3,GABRG3,NDN |
Renal and Urological Disease | 2.45E-01 | GABRB3 |
Reproductive System Development | 4.07E-03 | UBE3A |
Reproductive System Disease | 8.57E-03 - 5.87E-03 | MKRN3, UBE3A |
Respiratory Disease | 1.07E-02 - 5.97E-04 | GABRA5,GABRB3,GABRG3, MKRN3, SNRPN |
Skeletal and Muscular Disorders | 8.12E-03 - 1.40E-08 | GABRA5,GABRB3,GABRG3 |
Tissue Morphology | 5.26E-06 - 8.57E-03 | GABRA5,GABRB3,UBE3A |