Figure 1
From: Evaluation of chronic lymphocytic leukemia by BAC-based microarray analysis
Microarray results for case 1. (A) Single-copy loss of probes at 11q14.1q11.23.2, approximately 28.9 Mb in size. This deletion interval includes the ATM locus. Probes are ordered on the x axis according to physical mapping positions, with the most distal p-arm probes on the left and the most distal q-arm probes on the right. The blue line represents the ratios for each clone from the first experiment (control/patient), and the pink line represents the ratios for each clone obtained from the second experiment in which the dyes have been reversed (patient/control). The yellow shaded region shows a deletion at 11p11.2p11.12 with a single BAC clone showing apparent homozygous deletion over the gene PTPRJ. Results are visualized using Genoglyphix (Signature Genomics). (B) Single-copy loss of probes at 13q14.2q14.3, approximately 1.8 Mb in size. This deletion interval includes the RB1 locus. Probes are arranged as in (A).