On the paternal origin of trisomy 21 Down syndrome

Table 1 Results from fluorescent in situ hybridisation (FISH) in fetal testis using two chromosome 21-specific probes (red and green)

*One of these nuclei contained only one chromosome 18 signal and was interpreted as having either monosomy 21 together with monosomy 18 or being haploid; the remaining showing two chromosome 18 signals were recorded as either false negative monosomy 21 (due to somatic pairing) or true monosomy 21 [91, 92].
**These nuclei contained two chromosome 18 signals and were also recorded as false negative monosomy 21 (due to somatic pairing) or true monosomy 21[91, 92].
#This nucleus had 3 × 18 signals and was recorded as being triploid.

ISSN: 1755-8166