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Figure 2 | Molecular Cytogenetics

Figure 2

From: MODY-like diabetes associated with an apparently balanced translocation: possible involvement of MPP7 gene and cell polarity in the pathogenesis of diabetes

Figure 2

A. Sequences of PCR products from junctions aligned to reference human genome sequence. Upper case, chromosome 10 sequences. Lower case, chromosome 7 sequences. Upper case italics, origin unknown. B. UCSC Genome Browser tracks showing genes flanking the translocation breakpoints (arrows) and BAC clones used for FISH. C. FISH showing three signals for chromosome 7 (left) and chromosome 10 (right) BAC probes shown in B. D. Cartoon illustrating orientation of flanking genes and relative distances from translocation breakpoints.

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Molecular Cytogenetics

ISSN: 1755-8166