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Table 1 Clinically significant aberrations

From: Prenatal diagnosis of ultrasound soft markers in a single medical center of mainland China

 

Single USM

Multiple USMs

Total No. (%)

Euploid (n, %)

251 (73.39%)

91 (26.61%)

342

Total (n, %)

8 (3.09%)A

8 (8.08%)B

16 (4.47%)

Chromosomal syndrome disease (n, %)

4 (1.54%)

5 (5.05%)

9 (2.51%)

P/LP CVNs

 ≥ 10 Mb (n, %)

1 (0.39%)

1 (1.01%)

2 (0.56%)

 < 10 Mb (n, %)

3 (1.16%)

2 (2.02%)

5 (1.40%)

Total (n, %)

259 (72.3%)

99 (27.7%)

358

  1. Chi-squared (X2) test was applied to compare chromosomal aberrations between the 2 groups, P = 0.049. CVN Copy number variants; P/LP Pathogenic/likely pathogenic; USM Ultrasound soft marker