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Table 6 Summary of the findings of PPVs in SCAs

From: Positive predictive value estimates for noninvasive prenatal testing from data of a prenatal diagnosis laboratory and literature review

Reports

Country

NIPT cases

NIPT positive SCAs cases/Validated

PPV

45X

XXX

XXY

XYY

Xue [9]

China

57,204

295/NA

19.4

55.6

55.2

85.7

Liang [13]

China

94,085

390/390 (100)

25.8

61.7

82.9

75

Xu [28]

China

32,931

140/101 (72.1)

26.1

85

85

68.8

Deng [29]

China

50,301

308/182 (59.1)

18.4

44.4

39.3

75

Xu [16]

China

31,515

225/143 (63.6)

26

65.2

75

83.3

Fiorentino [21]

Italy

12,078

48/36 (75.0)

58.3

93.3

85.7

100

Garshasbi [25]

Iran

11,223

29/29 (100)

66.7

66.7

80

100

La Verde [26]

Italy

36,456

145/135 (93.1)

85.2

83.3

87.5

100

Soster [27]

USA

53,099

556/193 (34.7)

55.3

70.8

95.8

100

Lüthgens [30]

Germany

66,203

351/144 (41.0)

29

29.7

57.5

80