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Table 4 Cases of TP and FP distributions in different risk groups

From: Positive predictive value estimates for noninvasive prenatal testing from data of a prenatal diagnosis laboratory and literature review

Group

Total

True Positive

False Positive

PPV (%)

P value

All aneuploides

     

 Low risk

100

32

68

32.0

 

 Moderate risk

91

36

55

39.6

0.276

 High risk-one factor

189

102

87

54.0

< 0.001

 High risk-two factors or more

88

77

11

87.5

< 0.001

T21/T18/T13

     

 Low risk

33

12

21

36.4

 

 Moderate risk

35

20

15

57.1

0.086

 High risk-one factor

80

58

22

72.5

< 0.001

 High risk-two factors or more

69

67

2

97.1

< 0.001

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Molecular Cytogenetics

ISSN: 1755-8166