Table 2 Cases of TP FP distribution in different types of aneuploides
NIPT positive result | Cases n (%) | True positive | False positive | PPV (%) | FPR (%) |
|---|---|---|---|---|---|
T21 | 144 | 124 | 20 | 86.1 | 13.9 |
T18 | 45 | 26 | 19 | 57.8 | 42.2 |
T13 | 28 | 7 | 21 | 25.0 | 75.0 |
SCAs | 146 | 60 | 86 | 41.1 | 58.9 |
 Monosomy X | 40 | 8 | 32 | 20.0 | 80.0 |
 XXX | 17 | 4 | 13 | 23.5 | 76.5 |
 XXY | 16 | 11 | 5 | 68.8 | 25.0 |
 XYY | 8 | 5 | 3 | 62.5 | 37.5 |
RCAs | 53 | 9 | 44 | 17.0 | 83.0 |
CNVs | 52 | 21 | 31 | 40.4 | 59.6 |
Total | 468 | 247 | 221 | 52.8 | 47.2 |