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Table 3 Association between clinical information and the frequency of chromosomal abnormalities

From: Comprehensive analysis of early pregnancy loss based on cytogenetic findings from a tertiary referral center

 

Abnormal karyotype (n, %)

Viable autosomal trisomy (n, %)

Monosomy X (n, %)

Maternal age (years) (N = 1252)

≤ 29 (n = 537)

279, 52.0%,

24, 4.5%

34, 6.3%

30–34 (n = 452)

230, 50.9%

24, 5.3%

27, 6.0%

35–39 (n = 201)

115, 57.2%,

14, 7.0%

11, 5.5%

≥ 40 (n = 62)

43, 69.4%,

12, 19.4%

3, 4.8%

p

< 0.05

< 0.05

> 0.05

Normal live birth history (N = 895)

Yes (n = 185)

113, 61.1%

12, 6.5%

11, 5.9%

No (n = 710)

373, 52.5%

50, 7.0%

41, 5.8%

p

< 0.05

> 0.05

> 0.05

Previous miscarriage (N = 895)

0 (n = 273)

146, 53.5%

20, 7.3%

11, 4.0%

1–2 (n = 505)

271, 53.8%

40, 7.9%

33, 6.5%

≥ 3 (n = 117)

69, 59.0%

2, 1.7%

8, 6.8%

p

> 0.05

< 0.05

> 0.05

Mode of conception (N = 895)

Assisted conception (n = 115)

57, 49.0%

8, 7.0%

1, 0.9%

Natural conception (n = 780)

429, 55.0%

54, 6.9%

51,6.5%

P

> 0.05

> 0.05

< 0.05