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Fig. 2 | Molecular Cytogenetics

Fig. 2

From: Molecular and phenotypic characteristics of 15q24 microdeletion in pediatric patients with developmental disorders

Fig. 2

Columns of MLPA P245 results. X-axis represents MLPA probes. Y-axis represents probe dosage ratio. The blue line indicates probe dosage ratio of 1.35, and ratio above this line represents duplication. The red line indicates probe dosage ratio of 0.65, and ratio below this line represents deletion. Ratios between 0.85 and 1.15 are considered as normal. A A control with normal copy probes. B Case 1 carries CYP1A1-2 homozygous deletion. C Mother of case 1 carries CYP1A1-2 heterozygous deletion. D Case 3 carries SEMA7A-11 heterozygous deletion. E Case 4 carries CYP1A1-2 and SEMA7A-11 heterozygous deletion. MLPA: Multiplex ligation-dependent probe amplification

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