Differentially accessible, single copy sequences form contiguous domains along metaphase chromosomes that are conserved among multiple tissues

Table 1 Aggregated sc FISH probes and characteristics

Chromosome location	Domain Name [total length in bp]	Probe Name	Probe Genomic Coordinates [GRCh37/hg19]	Genomic Position*
1p36	N/A	3.3_1p36	chr1:1,171,789–1,175,143	Intergenic
2p23.1	XDH [25,454]	XDH_tel9263	chr2:31,545,815–31,547,924	Intergenic
		XDH_tel2386	chr2:31,551,816–31,554,801	Intergenic
		**XDH_IVS30-IVS27**	chr2:31,568,769–31,571,269	XDH
3p24.3	HMGB1P5 [39,731]	**ZNF385D_cen640649**	chr3:22,433,351–22,436,333	Intergenic
3p24.3	HMGB1P5 [39,731]	ZNF385D_cen678130	chr3:22,470,832–22,473,082	Intergenic
12p12.3	FGF6 [16,048]	**FGF6_tel4492**	chr12:4,537,157–4,538,816	Intergenic
12p12.3	FGF6 [16,048]	FGF6_IVS2	chr12:4,549,776–4,553,205	FGF6
15q21.1	N/A	DUOX1_IVS1-IVS3^a	chr15: 45,422,890–45,424,597	DUOX1
15q22.2	TPM1 [16,034]	TPM1_IVS5-IVS8	chr15:63,353,573–63,355,980	TPM1
		**TPM1_IVS8**	chr15:63,357,346–63,360,645	TPM1
		TPM1_tel3200	chr15:63,367,314–63,369,607	Intergenic
15q24.1	COX5A [109,970]	**SCAMP2_IVS7-IVS4**	chr15:75,142,349–75,145,350	SCAMP2
		SCAMP2_IVS1	chr15:75,161,783–75,163,308	SCAMP2
		COX5A_tel20181	chr15:75,250,595–75,252,319	Intergenic
20q13.3	HMGB1P1 [129,583]	RBM38_tel25076	chr20:56,009,465–56,011,485	Intergenic
		**CTCFL_cen34302**	chr20:56,033,167–56,036,719	Intergenic
		PCK1_cen13065	chr20:56,119,569–56,123,101	Intergenic
		PCK1_cen209-IVS6	chr20:56,135,957–56,139,048	PCK1

bp = base pair
^*Genomic position refers to the target sequence hybridized by sc FISH probe. Intergenic refers to a sc probe target between genes or outside of a gene. A gene name indicates that the sc probe target is within that given gene including exons and introns
Bolded probe names indicate the anchor probe (initial DA probe identified) from which neighboring sc probes were developed,
^aused in tissue conservation study not domain analysis

ISSN: 1755-8166