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Table 1 Prenatal diagnosis results of fourteen T16 cases predicted by NIPT

From: Outcomes of pregnancies with trisomy 16 mosaicism detected by NIPT: a series of case reports

Case Age Gestational week at NIPT NIPT Z score NIPT result Prenatal diagnosis
karyotype CMA
1 43 13 +  11.345 T16 mos47,XN, + mar[8]/46,XN[14] arr[hg19]4q34.3(178130290–179860825)*3 16p11.2q11.2(30995273–46786489)*3
2 35 18 17.824 T16 mos47,XN, + 16(4)/46,XN(17) arr(16) × 2–3
3 32 18 +  31.503 T16 mos47,XN, + 16(1)/46,XN(19) arr(16) × 2–3
4 28 25 8.629 T16 mos47,XN, + 16(1)/46,XN(80) arr(16) × 2–2.3
5 36 17 +  9.317 T16 / LOH in 16p13.3-p12.3 and 16q23.3-q24.3
6 23 16 17.542 T16 46,XN arr(1–22) × 2
7 29 21 +  7.791 T16 46,XN arr(1–22) × 2
8 34 13 13.304 T16 / arr(1–22) × 2
9 27 19 +  7.874 T16 46,XN /
10 33 18 +  22.812 T16 46,XN arr(1–22) × 2
11 31 13 22.295 T16 / arr(1–22) × 2
12 39 17 9.33 T16 mosaicism 46,XN /
13 30 15 15.14 T16 / arr(1–22) × 2
14 26 18 7.98 T16 mosaicism 46,XN /