Molecular Cytogenetics

Table 1 The correlation study between maternal age and fetal SCAs (including 45,X, 47,XXY, 47,XXX and 47,XYY) from previously published studies

From: The correlation between maternal age and fetal sex chromosome aneuploidies: a 8-year single institution experience in China

Diagnostic center	Number of pregnancies tested	Number with maternal age		Maternal age specific rates (%) for SCAs				References
Diagnostic center	Number of pregnancies tested	≥ 35 years	< 35 years	45,X	47,XXY	47,XXX	47,XYY	References
Europe and outside Europe	52,965	52,965	0	Negative correlation	Relevant	Relevant	Irrelevance	[9]
China	46,258	46,258	0	Irrelevance	Relevant	Relevant	Irrelevance	[10]
Italy	88,965	51,758	37,207	Borderline significance	Relevant	Relevant	Borderline significance	[11]
South Korea	15,381	15,381	0	Relevant	Relevant	Relevant	–	[12]

Maternal age was recorded at amniocentesis, except for that by Kim et al. [12], in which maternal age was recorded at excepted date of delivery. In each of the studies, amninocentesis was performed on the sole indication of maternal age

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ISSN: 1755-8166

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