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Table 1 The correlation study between maternal age and fetal SCAs (including 45,X, 47,XXY, 47,XXX and 47,XYY) from previously published studies

From: The correlation between maternal age and fetal sex chromosome aneuploidies: a 8-year single institution experience in China

Diagnostic center Number of pregnancies tested Number with maternal age Maternal age specific rates (%) for SCAs References
≥ 35 years < 35 years 45,X 47,XXY 47,XXX 47,XYY
Europe and outside Europe 52,965 52,965 0 Negative correlation Relevant Relevant Irrelevance [9]
China 46,258 46,258 0 Irrelevance Relevant Relevant Irrelevance [10]
Italy 88,965 51,758 37,207 Borderline significance Relevant Relevant Borderline significance [11]
South Korea 15,381 15,381 0 Relevant Relevant Relevant – [12]
  1. Maternal age was recorded at amniocentesis, except for that by Kim et al. [12], in which maternal age was recorded at excepted date of delivery. In each of the studies, amninocentesis was performed on the sole indication of maternal age
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Molecular Cytogenetics

ISSN: 1755-8166