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Fig. 5 | Molecular Cytogenetics

Fig. 5

From: Chinese hamster ovary cell line DXB-11: chromosomal instability and karyotype heterogeneity

Fig. 5

The most frequent clonal ASR. a Derivative variants of mar2 either with additional material on the long arm (mar24) or with deletions of the long arm (shown by lines). b G- and C- banded chromosomes 8, add(8)(q11)1 and mar22. c Deletion of the long arm of chromosome add(8)(q11), add(8)(q11)2 and mar24. d der(1)(1pter → 1q42::4q26 → 4qter) and der(4)(4pter → 4q11::4q12 → 4q26::1q42 → 1qter) resulting from balanced translocation of chromosomes 1 and del(4)(q11q12), G- banding and Ag-staining. e der(5)(5pter → 5q28::8q25 → 8qter) and der(8)(8pter → 8q25::5q28 → 5qter) resulting from balanced translocation of chromosomes 5 and 8, and add(5)(?::p14 → qter) and deletion of the short arm of mar1, mar11, G- banding and Ag-staining. f Chromosomes 5 and del(5)(p11), G- banding and Ag-staining. g del(8)(:p13 → pter) and derivative chromosome mar41, G- banding and Ag-staining. h der(3)1 resulting from interstitial deletion of the long arm of chromosome der(3). i, j der(4)(?::4p33 → 4q11::4q12 → 4qter) and der(5)(?::5p12 → 5qter) resulting from the translocation of the long arm of mar3 to chromosomes del(4) (i) or 5 (j), and mar31. Arrows indicate ASR of normal chromosomes of the main SVK. Double arrows indicate ASR of structurally rearranged chromosomes of the main SVK

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