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Table 1 Oncogenes and tumor suppressor genes (TSG), related to human BC [20, 21] and their involvement in gains or loss of copy numbers in JC cell line

From: Cytogenomic characteristics of murine breast cancer cell line JC

Oncogenes and TSGs Gene loci in human JC
NRAS 1p13~22 no CNV
MSH2 2p22 loss
RAF1 3p25 no CNV
RARβ2 3p24 no CNV
MLH1 3p21 no CNV
APC 5q21 no CNV
MYB 6q22-q23 loss
IGFII-R 6q26 no CNV
MYC 8q24 gain
CDKN2A (p16INK4) 9p21 no CNV
PTEN 10q23 loss
HRAS 11p15.5 loss
FGF3 11q13 loss
CCND1 11q13 loss
ATM 11q22 no CNV
CDKN1B (p27kip1) 12p13 no CNV
KRAS2 12p12.1 no CNV
BRCA2 13q12 loss
Rb1 13q14 no CNV
CDH1 (E-cadherin) 16q22 no CNV
TP53 (p53) 17p13 no CNV
BRCA1 17q21 no CNV
ERBB2 17q21 no CNV
SERPINB5 (maspin) 18q21 loss
STK11 (LKB1) 19p13 loss
SUM of concordance in CNVs of potentially affected regions 10/25
  1. CNV copy number variant