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Table 2 Relationship between RB1 gene deletion and disease stage, treatment status, β2 microglobulin level, 13q deletion rate and type

From: Which prognostic marker is responsible for the clinical heterogeneity in CLL with 13q deletion?

 

RB1 gen deletion

Total

p value

Negative n (%)

Positive n (%)

RAI stage

    

 0, 1, 2

25 (54)

21 (46)

46

p > 0.05

 3, 4

9 (64)

5 (36)

14

 

 Total

34

26

60

 

Treatment

    

 Positive

15 (62)

8 (35)

23

p > 0.05

 Negative

24 (58)

17 (42)

41

 

 Total

39

25

64

 

β2 microglobuline

    

 < 3.5 mg/dl

11 (61)

7 (39)

18

p > 0.05

 > 3.5 mg/dl

9 (60)

6 (40)

15

 

 Total

20

13

33

 

13q deletion rate

    

 < 80%

33 (63)

19 (37)

52

p > 0.05

 > 80%

8 (50)

8 (50)

16

 

 Total

41 (60)

27 (40)

68

 

 < 70%

23 (60,5)

15 (39,5)

38

p > 0.05

 > 70%

8 (42)

11 (58)

19

 

 Total

31 (54)

26 (46)

57

 

 < 60%

19 (59)

13 (41)

32

p > 0.05

 > 60%

12 (48)

13 (52)

25

 

 Total

31 (54)

26 (46)

57

 

Deletion type

    

 Monoallel

37 (59)

26 (41)

63

p > 0.05

 Biallel

4 (80)

1 (20)

5

 

 Total

41

27

68