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Table 2 Results of FISH for other derivative chromosomes

From: Detailed molecular cytogenetic characterisation of the myeloid cell line U937 reveals the fate of homologous chromosomes and shows that centromere capture is a feature of genome instability

Chromosome band Chromosome position (GRCh38) Marker/clone Chromosome
psu dic(3;1) del(1)(q11) der(5)t(1;5) der(5)t(5;13)
1 centromere    + (inactivea) +   
5q11.1 5:50139424-50285096 RP11-185I4     (+)
5q11.1 5:50768911-50961846 RP11-317O24    + + (15/20)/- (5/20) metaphases
+ (69/100)/- (31/100) interphases       
5q11.2 5:57029637-57212477 RP11-101B14    + + (15/20)/- (5/20) metaphases
5q11.2 5:58287078-58423150 RP11-313I12    + +
Chromosome band Chromosome position (GRCh38) Marker/clone Chromosome
Cytogenetically normal 7 (one copy) Normal 7 (other 2 or 3 copies) der(7)t(6;7)(q27;q21.12) or del(7)(q22.1q34)
7p15 7:24505360-24515863 RP11-343P21 ++ + +
Chromosome band Chromosome position (GRCh38) Marker/clone Chromosome
Cytogenetically normal 8 (one copy) Normal 8 (other 2 copies)
8p 8:475607-658638 RP11-800L13 ++ +
  1. Each + represents a signal intensity equivalent to one copy on the normal chromosome; ++ represents a double-strength signal; (+) represents reduced intensity signal
  2. aAs inferred by the absence of a centromeric constriction