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Table 1 Results of FISH for derivative chromosomes containing chromosome 20 segments

From: Detailed molecular cytogenetic characterisation of the myeloid cell line U937 reveals the fate of homologous chromosomes and shows that centromere capture is a feature of genome instability

1a Abnormal chromosome
Band Chr position (GRCh38) Marker/clone der(11)t(11;16;20) der(20)t(15;20)
11 centromere   D11Z1 +
11q23.3 11:118436490-118525221 KMT2A (MLL)
11q24.3 11:128311087-128485203 RP11-754N12 (ETS1) +
11q24.3 11:128694094-128812000 FLI1 +
16p13.11 16:15703135-15857030 MYH11 +
15q14 15:37089671-37297139 RP11-597G23 +a  
15q21.2 15:51495000-51629079 RP11-607G03 ++a  
15q22.2 15:60041031-60218374 RP11-366L09 (+)b  
15q25.1 15:80970069-81137763 RP11-775C24 ++a  
20p11.21 20:22409751-22462800 RP11-500O11 ++++b
20p11.21 20:22756464-22940284 RP11-755M18 +++b
20p11.21 20:23530430-23671508 RP11-218C14 ++b
20:24130923-24332313 RP11-717H21 +
20:24568986-24763965 RP11-580L12 +
20:25124608-25306738 RP11-156D15 +
20:25306022-25435715 RP11-384D7 +
20p11.1 20:25925848-26084581 RP11-269F15 +
20 centromere   D20Z1 +
20q11.21 20:31245645-31409837 RP11-602P9 +
20:31435456-31585732 RP11-802B20 +
20:31483476-31684958 RP11-363M16 (+) +
20:31592650-31760766 RP11-702M08 + +
20:31705215-31874074 RP11-243J16 + +
20:31902727-32053101 RP11-71I02 (+) +
20:31935170-32131327 RP11-620H13 (+) +
20:32022592-32204778 RP11-483M19 +
20:32385910-32580055 RP11-724J12 +
20:33132629-33305883 RP11-49G10 +
20q11.22 20:33458641-33609412 RP11-120F10
20:33747044-33935043 RP11-541L2
20:34110945-34261427 RP11-642P13
20q12 20:42201817-42202000 D20S108
  1. Each + represents a signal intensity equivalent to one copy on the normal chromosome. (+) represents reduced intensity signal. Positions for each BAC are those given in ensembl.org archives converted to GRCh38 co-ordinates. The order of chromosome 15 and 20 elements in the der(20)t(15;20) is derived from FISH and is described in the karyotype (Table 3)
  2. aVery faint signal—the breakpoint is at distal end of this clone
  3. bOne copy of each is present in the long arm of the der(20) and the additional copies are in the short arm