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Fig. 2 | Molecular Cytogenetics

Fig. 2

From: Detailed molecular cytogenetic characterisation of the myeloid cell line U937 reveals the fate of homologous chromosomes and shows that centromere capture is a feature of genome instability

Fig. 2

M-BAND images for chromosomes 6 and 20 for U937 chromosomes. a XCyte 6 images. Left to right, M-BAND 6 image from a metaphase with a der(6)del(6)dup(6), (top three chromosomes), and a der(7) from a different metaphase (bottom chromosome). Left to right, five single colour galleries, fluorescence intensity profiles. The closed white arrow points to a thin band in the aqua channel (brightened to make it visible in the image) of the der(6)t(2;6), showing that this chromosome has a more distal breakpoint (i.e. closer to the telomere of the short arm) than the der(6)del(6)dup(6), which does not have any aqua signal. The expanded red signal in the der(6)del(6p)dup(6) reveals amplification of 6p12-> 6p21 material (red arrow). b XCyte 20 images. Left to right, M-BAND image, fluorescence intensity profiles showing the presence of chromosome 20 material in the der(20)t(15;20) and the der(11)t(11;16;20)

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Molecular Cytogenetics

ISSN: 1755-8166