Table 2 The four tumor suppressor genes most often involved in human MM acc. to [7,8,9,10,11,12,13,14,15,16], being deleted and/or mutated there are compared for copy number variant observed in the three studied cell lines
From: Cytogenomic characterization of three murine malignant mesothelioma tumor cell lines
Human gene/murine homologue | AB1 | AB22 | AC29 |
|---|---|---|---|
BAP1 deletion 3p21.1 | (+) | + | No CNV |
CDKN2A deletion 9p21.2 | No CNV | No CNV | No CNV |
TP53 deletion 17p13.1 | No CNV | No CNV | No CNV |
NF2 deletion 22q12.2 | No CNV | No CNV | No CNV |