Skip to main content
Fig. 3 | Molecular Cytogenetics

Fig. 3

From: Chromosomal instability associated with adverse outcome: a case report of patient with Nijmegen breakage syndrome and rapidly developed T-NHL with complex karyotype

Fig. 3

Images of the FISH results revealing chromosomal aberrations. (a) Image of the FISH results with the whole chromosome painting (WCP) 1 and 3 probes (Cytocell Ltd., Oxford Gene Technology, Cambridge, United Kingdom) revealing t(1;3). (b) Chromosome analysis demonstrating derivative chromosomes 3 der(3)t(1;3)(q12;q22) and chromosome 1. (c) Image of the FISH results with the LSI CSF1R/D5S23, D5S721 Dual Color probe (Vysis, Abbot Molecular, Illinois, USA) revealing del(5q33-q34). (d) Chromosome analysis demonstrating abnormal chromosome 5 with deletion of 5q33-q34. (e) Image of the FISH results with the STIL Break Apart Probe (Empire Genomics, New York, USA) revealing STIL duplication. (f) Image of the FISH results with WCP4 probe (Cytocell Ltd., Oxford Gene Technology, Cambridge, United Kingdom) revealing t(4;9). (g) Image of the FISH results with WCP5 and WCP10 probes (Cytocell Ltd., Oxford Gene Technology, Cambridge, United Kingdom) revealing t(5;10). (h) Image of the FISH results with WCP6 and WCP16 probes (Cytocell Ltd., Oxford Gene Technology, Cambridge, United Kingdom) revealing t(6;16). Images were captured by an Olympus BX41TF microscope equipped with a Jenoptik camera and analysed with Isis Software (MetaSystems)

Back to article page

Molecular Cytogenetics

ISSN: 1755-8166