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Fig. 4 | Molecular Cytogenetics

Fig. 4

From: Coexistence of recurrent chromosomal abnormalities and the Philadelphia chromosome in acute and chronic myeloid leukemias: report of five cases and review of literature

Fig. 4

Bone marrow karyotype and metaphase-FISH results of Case 4. a R-banded karyotype of case 4: 46,XY,t(3;21)(q26;q22),t(9;22)(q34;q11.2). Panels b-drepresent FISH analysis of metaphase cells corresponding to the karyotypes in panel a, b Metaphase FISH using dual color break apart probe EVI1 showing EVI1 rearrangement (split red/ green signal). c Corresponding R-banded metaphase. d Sequential FISH using BCR-ABL1 fusion (ABL1: red; BCR: green) probe on the same metaphase showing BCR-ABL1 fusion (ABL1: red; BCR: green)

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