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Table 4 Frequency of alterations according to characteristics of patients

From: Identifying novel genetic alterations in pediatric acute lymphoblastic leukemia based on copy number analysis

 

DMBT1 deletion

KIAA0125 amplification

PRDM16 deletion

Present

Ausent

Present

Absent

Present

Absent

NCI-HR

16

14

19

11

41

13

NCI-SR

46

8

31

23

1

29

p-value

0.0036*

0.6483

p < 0.001*

≤1 years

5

2

4

3

3

4

> 1 to ≤10 years

44

10

34

20

26

28

> 10 years

13

10

12

11

13

10

p-value 11

0.6131

0.9994

1

p-value 22

0.6693

1

0.6746

p-value 33

0.0433*

0.4497

0.6200

WBC > 50

16

5

16

5

8

13

WBC ≤ 50

46

17

34

29

34

29

p-value

1

0.0802

0.4568

Leucopenia

5

0

5

0

0

5

Leucocytosis

54

18

40

32

37

35

p-value

0.3336

0.0720

0.0554

Male

38

11

31

18

21

28

Female

24

11

19

16

21

14

p-value

0.4515

0.5002

0.1839

  1. NCI-HR NCI-High risk; NCI-SR NCI Standard risk; WBC White blood count. 1 ≤ 1 years versus > 1 to ≤10 years; 2 ≤ 1 years versus > 10 years; 3 > 1 to ≤10 years versus > 10 years. *Significant difference between groups with and without aberrations, p ≤ 0.05, Fisher’s exact test