From: Laundering CNV data for candidate process prioritization in brain disorders
Cluster name | Pathways |
---|---|
Neurodegenerative diseases | ● Neurodegenerative diseases |
Proteasome | ● Downregulation of TGF-beta receptor signaling |
Signaling by ERBB4 | ● Signaling by ERBB4 |
● Nuclear signaling by ERBB4 | |
Transcription regulation | ● SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
● RNA polymerase II repressing transcription factor binding | |
● RNA polymerase II activating transcription factor binding | |
Regulation of TP53 | ● Regulation of TP53 degradation |
● Regulation of TP53 activity through acetylation | |
● p53 binding | |
Signaling by NOTCH | ● Activated NOTCH1 transmits signal to the nucleus |
● Signaling by NOTCH2 | |
Senescence | ● Oncogene induced senescence |
Mitosis | ● Mitotic cytokinesis |
● Spindle pole | |
DNA repair | ● HDR through single strand annealing (SSA) |
● Nucleotide-excision repair, DNA damage recognition | |
Vesicles functioning | ● SNAP receptor activity |
Actin functioning | ● Stress fiber |
● Podosome | |
Macromolecular interactions | ● Insulin receptor binding |
● Protein kinase C binding | |
● Fibroblast growth factor receptor binding | |
● Core promoter sequence-specific DNA binding | |
● RNA polymerase II core binding | |
● Beta-amyloid binding | |
● Epidermal growth factor receptor binding | |
B cells functioning | ● B cell homeostasis |
● B cell apoptotic process |