Molecular cytogenetic analysis and genetic counseling: a case report of eight 46,XX males and a literature review

Table 1 Summary of the physical and clinical examinations of our patients

Case	Age	Height (cm)	Weight (kg)	Testicle volume (mL)		Serum levels					Male signs	Diagnosis	ART follow-up
Case	Age	Height (cm)	Weight (kg)	Left	Right	FSH	LH	E2	PRL	T	Male signs	Diagnosis	ART follow-up
1	23	165	49	2	2	N.A.	N.A.	N.A.	N.A.	N.A.	Sparse beard	Azoospermia	AID
2	36	171	57	2	2	45	29.6	19.27	196	3.9	Normal	Azoospermia	AID
3	28	166	60	2	2	18.8	14.1	33.36	269	4.7	Normal	Azoospermia	AID
4	32	169	50	1	1	45.4	28.5	31.8	219	5.4	Sparse beard	Azoospermia	N.A.
5	26	175	80	3	5	21.2	14.3	22.63	147	6.5	Normal	Azoospermia	N.A.
6	30	170	60	4	4	62.83	27.12	17.9	316.6	9.19	Normal	Azoospermia	N.A.
7	23	165	56	3	3	40.05	22.11	13.6	316.6	2.22	Normal	Azoospermia	N.A.
8	27	168	51	10	10	6.6	9.6	33.14	485	3.6	Normal	Azoospermia	N.A.

The reference values were obtained from electrochemiluminescence immunoassays (ECLIA) using Roche Elecsys1010 (Roche Diagnostics, Mannheim, Germany) according to the manufacturer’s instructions. N.A. Not available, ART Assisted reproductive technology, AID Artificial insemination by donor sperm
FSH (follicle-stimulating hormone): 1.5–12.4 mIU/ml; LH(luteinizing hormone): 1.7–8.5 mIU/ml; E2(estradiol): 28–248 pg/ml; PRL(prolactin): 86–258 uIU/ml; T(testosterone): 9.9–27.8 nmol/l

ISSN: 1755-8166