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Fig. 2 | Molecular Cytogenetics

Fig. 2

From: A case of acute promyelocytic leukemia variant with derivative chromosome 3 der(3)t(3;8) associated with 8q partial gain

Fig. 2

a Karyogram according to SNP-A analysis. Gain appears in green at the right of chromosome 8; b FISH analysis with RPN1/MECOM DF probe showing a normal pattern of hybridization on BM at diagnosis; c FISH analysis with MYC break-apart probe showing three c-myc alleles without breaking on BM at diagnosis; d FISH analysis with the centromere (CEP 8) probe on BM cells at diagnosis showing a normal pattern of hybridization; e characterization of der(3) by FISH with whole chromosome painting 3 (red) and 8 (green) on BM cells at diagnosis

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