Fig. 2
From: Detection of a balanced translocation carrier through trophectoderm biopsy analysis: a case report
Identified meiotic segregation patterns and consequent embryo genomic profiles from reciprocal translocation carrier. Chromosomes, involved in balanced translocation in the mother (a), form a quadrivalent structure during meiotic pairing (b). Upon chromosome segregation, normal, balanced and unbalanced oocytes were generated as a result alternate segregation, adjacent I and adjacent II segregation (c). Upon fertilization, these oocytes give rise to embryos with or without genomic imbalances, as was identified by PGT-A (d)