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Table 1 Chromosomal location, occurrence of breakpoint events (BP), odds ratio, located genes and association to fragile sites of the top-15 breakpoint regions. Genes that are associated with cancer in literature are marked with an asterisk

From: Genome reorganization in different cancer types: detection of cancer specific breakpoint regions

Chr Start End Cytoband BP in NMCE (20) BP in Tumors (111) Odds Ratio BP in CCLE (917) Genes Fragile Sites
1 118000001 118100001 1p12 0 23 10,68 4 MAN1A2
2 4900001 5000001 2p25.2 0 23 10,68 26 FRA2M
4 88700001 88800001 4q22.1 0 24 11,26 2 IBSP*, MPEP* FRA4F
5 45900001 46000001 5p12 0 24 11,26 1
5 46300001 46400001 5p11 0 26 12,47 81 FRA5I
7 11700001 11800001 7p21.3 0 24 11,26 5 THSD7A* FRA7L
7 37600001 37700001 7p14.1 0 23 10,68 0 NECAP1P1
7 103400001 103500001 7q22.1 1 23 4,97 1 RELN* FRA7F
8 43400001 43500001 8p11.1 0 25 11,86 2 FRA8I
8 43700001 43800001 8p11.1 0 32 16,46 48 FRA8I
8 47300001 47400001 8q11.1 0 23 10,68 1 FRA8I
9 141000001 141100001 9q34.3 1 48 14,48 321 CACNA1B* FRA9N
13 35900001 36000001 13q13.3 0 23 10,68 1 NBEA*
13 115100001 115106996 13q34 3 40 3,19 210 FRA13I
14 20400001 20500001 14q11.2 3 36 2,72 61 OR4K1, OR4K5, OR4K14, OR4K15 FRA14D