TY - JOUR AU - Vogelstein, B. AU - Kinzler, K. W. PY - 1993 DA - 1993// TI - The multistep nature of cancer JO - Trends Genet VL - 9 UR - https://doi.org/10.1016/0168-9525(93)90209-Z DO - 10.1016/0168-9525(93)90209-Z ID - Vogelstein1993 ER - TY - JOUR AU - Hanahan, D. AU - Weinberg, R. A. PY - 2011 DA - 2011// TI - Hallmarks of cancer: the next generation JO - Cell VL - 144 UR - https://doi.org/10.1016/j.cell.2011.02.013 DO - 10.1016/j.cell.2011.02.013 ID - Hanahan2011 ER - TY - JOUR AU - Loeb, L. A. AU - Loeb, K. R. AU - Anderson, J. P. PY - 2003 DA - 2003// TI - Multiple mutations and cancer JO - Proc Natl Acad Sci VL - 100 UR - https://doi.org/10.1073/pnas.0334858100 DO - 10.1073/pnas.0334858100 ID - Loeb2003 ER - TY - JOUR AU - Osborne, C. PY - 2004 DA - 2004// TI - Oncogenes and tumor suppressor genes in breast Cancer: potential diagnostic and therapeutic applications JO - Oncologist VL - 9 UR - https://doi.org/10.1634/theoncologist.9-4-361 DO - 10.1634/theoncologist.9-4-361 ID - Osborne2004 ER - TY - JOUR AU - Klein, A. AU - Guhl, E. AU - Zollinger, R. PY - 2005 DA - 2005// TI - Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast cancer formation in WAP-SVT/t transgenic animals JO - J Mol Med VL - 83 UR - https://doi.org/10.1007/s00109-004-0625-1 DO - 10.1007/s00109-004-0625-1 ID - Klein2005 ER - TY - JOUR AU - Foulds, L. PY - 1954 DA - 1954// TI - The experimental study of tumor progression: a review JO - Cancer Res VL - 14 ID - Foulds1954 ER - TY - JOUR AU - Shlien, A. AU - Malkin, D. PY - 2009 DA - 2009// TI - Copy number variations and cancer JO - Genome Med VL - 1 UR - https://doi.org/10.1186/gm62 DO - 10.1186/gm62 ID - Shlien2009 ER - TY - JOUR AU - Beroukhim, R. AU - Mermel, C. H. AU - Porter, D. PY - 2010 DA - 2010// TI - The landscape of somatic copy-number alteration across human cancers JO - Nature VL - 463 UR - https://doi.org/10.1038/nature08822 DO - 10.1038/nature08822 ID - Beroukhim2010 ER - TY - JOUR AU - Standfuß, C. AU - Pospisil, H. AU - Klein, A. PY - 2012 DA - 2012// TI - SNP microarray analyses reveal copy number alterations and progressive genome reorganization during tumor development in SVT/t driven mice breast cancer JO - BMC Cancer VL - 12 UR - https://doi.org/10.1186/1471-2407-12-380 DO - 10.1186/1471-2407-12-380 ID - Standfuß2012 ER - TY - JOUR AU - Redon, R. AU - Ishikawa, S. AU - Fitch, K. R. PY - 2006 DA - 2006// TI - Global variation in copy number in the human genome JO - Nature VL - 444 UR - https://doi.org/10.1038/nature05329 DO - 10.1038/nature05329 ID - Redon2006 ER - TY - JOUR AU - Malhotra, D. AU - Sebat, J. PY - 2012 DA - 2012// TI - CNVs: harbingers of a rare variant revolution in psychiatric genetics JO - Cell VL - 148 UR - https://doi.org/10.1016/j.cell.2012.02.039 DO - 10.1016/j.cell.2012.02.039 ID - Malhotra2012 ER - TY - JOUR AU - Zhang, F. AU - Khajavi, M. AU - Connolly, A. M. PY - 2009 DA - 2009// TI - The DNA replication FoSTeS/MMBIR mechanism can generate genomic, genic and exonic complex rearrangements in humans JO - Nat Genet VL - 41 UR - https://doi.org/10.1038/ng.399 DO - 10.1038/ng.399 ID - Zhang2009 ER - TY - JOUR AU - Sen, S. PY - 2000 DA - 2000// TI - Aneuploidy and cancer JO - Curr Opin Oncol VL - 12 UR - https://doi.org/10.1097/00001622-200001000-00014 DO - 10.1097/00001622-200001000-00014 ID - Sen2000 ER - TY - JOUR AU - Mitelman, F. AU - Johansson, B. AU - Mertens, F. PY - 2007 DA - 2007// TI - The impact of translocations and gene fusions on cancer causation JO - Nat Rev Cancer VL - 7 UR - https://doi.org/10.1038/nrc2091 DO - 10.1038/nrc2091 ID - Mitelman2007 ER - TY - JOUR AU - Meaburn, K. J. AU - Misteli, T. PY - 2008 DA - 2008// TI - Locus-specific and activity-independent gene repositioning during early tumorigenesis JO - J Cell Biol VL - 180 UR - https://doi.org/10.1083/jcb.200708204 DO - 10.1083/jcb.200708204 ID - Meaburn2008 ER - TY - JOUR AU - Klein, A. AU - Li, N. AU - Nicholson, J. M. PY - 2010 DA - 2010// TI - Transgenic oncogenes induce oncogene-independent cancers with individual karyotypes and phenotypes JO - Cancer Genet Cytogenet VL - 200 UR - https://doi.org/10.1016/j.cancergencyto.2010.04.008 DO - 10.1016/j.cancergencyto.2010.04.008 ID - Klein2010 ER - TY - JOUR AU - Pevzner, P. AU - Tesler, G. PY - 2003 DA - 2003// TI - Human and mouse genomic sequences reveal extensive breakpoint reuse in mammalian evolution JO - Proc Natl Acad Sci VL - 100 UR - https://doi.org/10.1073/pnas.1330369100 DO - 10.1073/pnas.1330369100 ID - Pevzner2003 ER - TY - JOUR AU - Nadeau, J. H. AU - Taylor, B. A. PY - 1984 DA - 1984// TI - Lengths of chromosomal segments conserved since divergence of man and mouse JO - Proc Natl Acad Sci VL - 81 UR - https://doi.org/10.1073/pnas.81.3.814 DO - 10.1073/pnas.81.3.814 ID - Nadeau1984 ER - TY - JOUR AU - Zhao, S. AU - Shetty, J. AU - Hou, L. PY - 2004 DA - 2004// TI - Human, mouse, and rat genome large-scale rearrangements: stability versus speciation JO - Genome Res VL - 14 UR - https://doi.org/10.1101/gr.2663304 DO - 10.1101/gr.2663304 ID - Zhao2004 ER - TY - JOUR AU - Murphy, W. J. PY - 2005 DA - 2005// TI - Dynamics of Mammalian Chromosome Evolution Inferred from Multispecies Comparative Maps JO - Science VL - 309 UR - https://doi.org/10.1126/science.1111387 DO - 10.1126/science.1111387 ID - Murphy2005 ER - TY - JOUR AU - Ruiz-Herrera, A. AU - Castresana, J. AU - Robinson, T. J. PY - 2006 DA - 2006// TI - Is mammalian chromosomal evolution driven by regions of genome fragility? JO - Genome Biol VL - 7 UR - https://doi.org/10.1186/gb-2006-7-12-r115 DO - 10.1186/gb-2006-7-12-r115 ID - Ruiz-Herrera2006 ER - TY - JOUR AU - Magenis, R. E. AU - Hecht, F. AU - Lovrien, E. W. PY - 1970 DA - 1970// TI - Heritable fragile site on chromosome 16: probable localization of haptoglobin locus in man JO - Science VL - 170 UR - https://doi.org/10.1126/science.170.3953.85 DO - 10.1126/science.170.3953.85 ID - Magenis1970 ER - TY - JOUR AU - Durkin, S. G. AU - Glover, T. W. PY - 2007 DA - 2007// TI - Chromosome fragile sites JO - Annu Rev Genet VL - 41 UR - https://doi.org/10.1146/annurev.genet.41.042007.165900 DO - 10.1146/annurev.genet.41.042007.165900 ID - Durkin2007 ER - TY - JOUR AU - Zlotorynski, E. AU - Rahat, A. AU - Skaug, J. PY - 2003 DA - 2003// TI - Molecular basis for expression of common and rare fragile sites JO - Mol Cell Biol VL - 23 UR - https://doi.org/10.1128/MCB.23.20.7143-7151.2003 DO - 10.1128/MCB.23.20.7143-7151.2003 ID - Zlotorynski2003 ER - TY - JOUR AU - Hecht, F. AU - Sutherland, G. R. PY - 1984 DA - 1984// TI - Fragile sites and cancer breakpoints JO - Cancer Genet Cytogenet VL - 12 UR - https://doi.org/10.1016/0165-4608(84)90132-8 DO - 10.1016/0165-4608(84)90132-8 ID - Hecht1984 ER - TY - JOUR AU - Yunis, J. J. AU - Soreng, A. L. PY - 1984 DA - 1984// TI - Constitutive fragile sites and cancer JO - Science VL - 226 UR - https://doi.org/10.1126/science.6239375 DO - 10.1126/science.6239375 ID - Yunis1984 ER - TY - JOUR AU - Bartkova, J. AU - Hořejší, Z. AU - Koed, K. PY - 2005 DA - 2005// TI - DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis JO - Nature VL - 434 UR - https://doi.org/10.1038/nature03482 DO - 10.1038/nature03482 ID - Bartkova2005 ER - TY - JOUR AU - Tsantoulis, P. K. AU - Kotsinas, A. AU - Sfikakis, P. P. PY - 2008 DA - 2008// TI - Oncogene-induced replication stress preferentially targets common fragile sites in preneoplastic lesions. A genome-wide study JO - Oncogene VL - 27 UR - https://doi.org/10.1038/sj.onc.1210989 DO - 10.1038/sj.onc.1210989 ID - Tsantoulis2008 ER - TY - JOUR AU - Debatisse, M. AU - Tallec, B. AU - Letessier, A. PY - 2012 DA - 2012// TI - Common fragile sites: mechanisms of instability revisited JO - Trends Genet VL - 28 UR - https://doi.org/10.1016/j.tig.2011.10.003 DO - 10.1016/j.tig.2011.10.003 ID - Debatisse2012 ER - TY - JOUR AU - Donahue, T. R. AU - Tran, L. M. AU - Hill, R. PY - 2012 DA - 2012// TI - Integrative survival-based molecular profiling of human pancreatic Cancer JO - Clin Cancer Res VL - 18 UR - https://doi.org/10.1158/1078-0432.CCR-11-1539 DO - 10.1158/1078-0432.CCR-11-1539 ID - Donahue2012 ER - TY - JOUR AU - Barretina, J. AU - Caponigro, G. AU - Stransky, N. PY - 2012 DA - 2012// TI - The Cancer cell line encyclopedia enables predictive modelling of anticancer drug sensitivity JO - Nature VL - 483 UR - https://doi.org/10.1038/nature11003 DO - 10.1038/nature11003 ID - Barretina2012 ER - TY - JOUR AU - Marzese, D. M. AU - Scolyer, R. A. AU - Huynh, J. L. PY - 2013 DA - 2013// TI - Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis JO - Hum Mol Genet VL - 23 UR - https://doi.org/10.1093/hmg/ddt420 DO - 10.1093/hmg/ddt420 ID - Marzese2013 ER - TY - JOUR AU - Xie, Z. h. i. h. u. i. AU - Nagarajan, V. i. j. a. y. a. r. a. j. AU - Sturdevant, D. a. n. i. e. l. E. AU - Iwaki, S. h. o. k. o. AU - Chan, E. u. n. i. c. e. AU - Wisch, L. a. u. r. a. AU - Young, M. i. c. h. a. e. l. AU - Nelson, C. e. l. e. s. t. e. M. AU - Porcella, S. t. e. p. h. e. n. F. AU - Druey, K. i. r. k. M. PY - 2013 DA - 2013// TI - Genome-wide SNP analysis of the Systemic Capillary Leak Syndrome (Clarkson disease) JO - Rare Diseases VL - 1 UR - https://doi.org/10.4161/rdis.27445 DO - 10.4161/rdis.27445 ID - Xie2013 ER - TY - JOUR AU - Gentleman, R. C. AU - Carey, V. J. AU - Bates, D. M. PY - 2004 DA - 2004// TI - Bioconductor: open software development for computational biology and bioinformatics JO - Genome Biol VL - 5 UR - https://doi.org/10.1186/gb-2004-5-10-r80 DO - 10.1186/gb-2004-5-10-r80 ID - Gentleman2004 ER - TY - JOUR AU - Olshen, A. B. AU - Venkatraman, E. S. AU - Lucito, R. PY - 2004 DA - 2004// TI - Circular binary segmentation for the analysis of array-based DNA copy number data JO - Biostatistics VL - 5 UR - https://doi.org/10.1093/biostatistics/kxh008 DO - 10.1093/biostatistics/kxh008 ID - Olshen2004 ER - TY - JOUR AU - Mrasek, K. AU - Schoder, C. AU - Teichmann, A. -. C. PY - 2010 DA - 2010// TI - Global screening and extended nomenclature for 230 aphidicolin-inducible fragile sites, including 61 yet unreported ones JO - Int J Oncol VL - 36 ID - Mrasek2010 ER - TY - JOUR AU - Smeets, D. F. AU - Scheres, J. M. AU - Hustinx, T. W. PY - 1986 DA - 1986// TI - The most common fragile site in man is 3p14 JO - Hum Genet VL - 72 UR - https://doi.org/10.1007/BF00291880 DO - 10.1007/BF00291880 ID - Smeets1986 ER - TY - STD TI - Kalinina T, Güngör C, Thieltges S, et al. Establishment and characterization of a new human pancreatic adenocarcinoma cell line with high metastatic potential to the lung. BMC Cancer; 10. Epub ahead of print 2010. DOI: https://doi.org/10.1186/1471-2407-10-295. ID - ref38 ER - TY - JOUR AU - Burdall, S. E. AU - Hanby, A. M. AU - Lansdown, M. R. J. PY - 2003 DA - 2003// TI - Breast cancer cell lines: friend or foe? JO - Breast Cancer Res VL - 5 UR - https://doi.org/10.1186/bcr577 DO - 10.1186/bcr577 ID - Burdall2003 ER - TY - JOUR AU - Kyriazis, A. P. AU - Kyriazis, A. A. AU - Scarpelli, D. G. AU - Fogh, J. AU - Rao, M. S. L. R. PY - 1982 DA - 1982// TI - Human pancreatic adenocarcinoma line Capan-1 in tissue culture and the nude mouse: morphologic, biologic, and biochemical characteristics JO - Am Assoc Pathol VL - 106 ID - Kyriazis1982 ER - TY - STD TI - Kyriazis AA, Kyriazis AP, Sternberg CN, Sloane NHLJ. Morphological, biological, biochemical, and karyotypic characteristics of human pancreatic ductal adenocarcinoma Capan-2 in tissue culture and the nude mouse. Cancer Res. 1986:5810–5. ID - ref41 ER - TY - JOUR AU - Thompson, S. L. AU - Compton, D. A. PY - 2011 DA - 2011// TI - Chromosomes and cancer cells JO - Chromosom Res VL - 19 UR - https://doi.org/10.1007/s10577-010-9179-y DO - 10.1007/s10577-010-9179-y ID - Thompson2011 ER - TY - JOUR AU - Vargas-Rondón, N. AU - Villegas, V. E. AU - Rondón-Lagos, M. PY - 2018 DA - 2018// TI - The role of chromosomal instability in cancer and therapeutic responses JO - Cancers (Basel) VL - 10 ID - Vargas-Rondón2018 ER - TY - STD TI - https://cgap.nci.nih.gov/Chromosomes/Mitelman. Accessed 5 MAY 2019. UR - https://cgap.nci.nih.gov/Chromosomes/Mitelman ID - ref44 ER - TY - JOUR AU - Marczok, S. AU - Bortz, B. AU - Wang, C. PY - 2016 DA - 2016// TI - Comprehensive analysis of genome rearrangements in eight human malignant tumor tissues JO - PLoS One VL - 11 UR - https://doi.org/10.1371/journal.pone.0158995 DO - 10.1371/journal.pone.0158995 ID - Marczok2016 ER - TY - JOUR AU - Shao, P. AU - Sun, D. AU - Wang, L. PY - 2017 DA - 2017// TI - Deep sequencing and comprehensive expression analysis identifies several molecules potentially related to human poorly differentiated hepatocellular carcinoma JO - FEBS Open Bio VL - 7 UR - https://doi.org/10.1002/2211-5463.12310 DO - 10.1002/2211-5463.12310 ID - Shao2017 ER - TY - JOUR AU - O’Neal, J. AU - Gao, F. AU - Hassan, A. PY - 2009 DA - 2009// TI - Neurobeachin (NBEA) is a target of recurrent interstitial deletions at 13q13 in patients with MGUS and multiple myeloma JO - Exp Hematol VL - 37 UR - https://doi.org/10.1016/j.exphem.2008.10.014 DO - 10.1016/j.exphem.2008.10.014 ID - O’Neal2009 ER - TY - JOUR AU - Xu, T. a. o. AU - Qin, R. o. n. g. AU - Zhou, J. i. n. x. u. AU - Yan, Y. o. n. g. AU - Lu, Y. i. c. h. e. n. g. AU - Zhang, X. i. a. o. p. i. n. g. AU - Fu, D. a. AU - Lv, Z. h. o. n. g. w. e. i. AU - Li, W. e. i. q. i. n. g. AU - Xia, C. h. u. n. y. a. n. AU - Hu, G. u. o. h. a. n. AU - Ding, X. u. e. h. u. a. AU - Chen, J. u. x. i. a. n. g. PY - 2012 DA - 2012// TI - High Bone Sialoprotein (BSP) Expression Correlates with Increased Tumor Grade and Predicts a Poorer Prognosis of High-Grade Glioma Patients JO - PLoS ONE VL - 7 UR - https://doi.org/10.1371/journal.pone.0048415 DO - 10.1371/journal.pone.0048415 ID - Xu2012 ER - TY - JOUR AU - Gao, Z. AU - Zhao, Y. AU - Geng, Q. PY - 2017 DA - 2017// TI - Regulatory roles of miRNA-758 and matrix extracellular phosphoglycoprotein in cervical cancer JO - Exp Ther Med VL - 14 UR - https://doi.org/10.3892/etm.2017.4887 DO - 10.3892/etm.2017.4887 ID - Gao2017 ER - TY - JOUR AU - Dou, A. AU - Wang, Z. AU - Zhang, N. PY - 2017 DA - 2017// TI - Loss of reelin suppresses cell survival and mobility in non-Hodgkin lymphoma JO - Oncol Rep VL - 37 UR - https://doi.org/10.3892/or.2017.5626 DO - 10.3892/or.2017.5626 ID - Dou2017 ER - TY - JOUR AU - Wiech, T. AU - Hoxha, E. AU - Schröder, C. PY - 2016 DA - 2016// TI - THSD7A expression in human cancer JO - Genes Chromosom Cancer VL - 56 ID - Wiech2016 ER - TY - JOUR AU - Zhou, X. AU - Wang, W. AU - Zhang, S. PY - 2017 DA - 2017// TI - CACNA1B (ca v 2.2) overexpression and its association with Clinicopathologic characteristics and unfavorable prognosis in non-small cell lung Cancer JO - Dis Markers VL - 2017 ID - Zhou2017 ER - TY - JOUR AU - Olsson, M. AU - Beck, S. AU - Kogner, P. PY - 2016 DA - 2016// TI - Genome-wide methylation profiling identifies novel methylated genes in neuroblastoma tumors JO - Epigenetics VL - 11 UR - https://doi.org/10.1080/15592294.2016.1138195 DO - 10.1080/15592294.2016.1138195 ID - Olsson2016 ER - TY - JOUR AU - Glover, T. W. AU - Berger, C. AU - Coyle, J. PY - 1984 DA - 1984// TI - DNA polymerase α inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes JO - Hum Genet VL - 67 UR - https://doi.org/10.1007/BF00272988 DO - 10.1007/BF00272988 ID - Glover1984 ER - TY - JOUR AU - Glover, T. W. AU - Wilson, T. E. AU - Arlt, M. F. PY - 2017 DA - 2017// TI - Fragile sites in cancer: more than meets the eye JO - Nat Rev Cancer VL - 17 UR - https://doi.org/10.1038/nrc.2017.52 DO - 10.1038/nrc.2017.52 ID - Glover2017 ER - TY - JOUR AU - Finnis, M. AU - Dayan, S. AU - Hobson, L. PY - 2005 DA - 2005// TI - Common chromosomal fragile site FRA16D mutation in cancer cells JO - Hum Mol Genet VL - 14 UR - https://doi.org/10.1093/hmg/ddi144 DO - 10.1093/hmg/ddi144 ID - Finnis2005 ER - TY - JOUR AU - Smith, D. I. AU - Zhu, Y. AU - McAvoy, S. PY - 2006 DA - 2006// TI - Common fragile sites, extremely large genes, neural development and cancer JO - Cancer Lett VL - 232 UR - https://doi.org/10.1016/j.canlet.2005.06.049 DO - 10.1016/j.canlet.2005.06.049 ID - Smith2006 ER - TY - JOUR AU - Saldivar, J. C. AU - Bene, J. AU - Hosseini, S. A. PY - 2013 DA - 2013// TI - Characterization of the role of Fhit in suppression of DNA damage JO - Adv Biol Regul VL - 53 UR - https://doi.org/10.1016/j.jbior.2012.10.003 DO - 10.1016/j.jbior.2012.10.003 ID - Saldivar2013 ER - TY - JOUR AU - Cox, C. AU - Bignell, G. AU - Greenman, C. PY - 2005 DA - 2005// TI - A survey of homozygous deletions in human cancer genomes JO - Proc Natl Acad Sci VL - 102 UR - https://doi.org/10.1073/pnas.0408593102 DO - 10.1073/pnas.0408593102 ID - Cox2005 ER - TY - JOUR AU - Dunham, M. J. AU - Badrane, H. AU - Ferea, T. PY - 2002 DA - 2002// TI - Characteristic genome rearrangements in experimental evolution of Saccharomyces cerevisiae JO - Proc Natl Acad Sci VL - 99 UR - https://doi.org/10.1073/pnas.242624799 DO - 10.1073/pnas.242624799 ID - Dunham2002 ER - TY - JOUR AU - Tang, Y. -. C. AU - Amon, A. PY - 2013 DA - 2013// TI - Gene copy-number alterations: a cost-benefit analysis JO - Cell VL - 152 UR - https://doi.org/10.1016/j.cell.2012.11.043 DO - 10.1016/j.cell.2012.11.043 ID - Tang2013 ER - TY - JOUR AU - Meaburn, K. J. PY - 2016 DA - 2016// TI - Spatial genome organization and its emerging role as a potential diagnosis tool JO - Front Genet VL - 7 UR - https://doi.org/10.3389/fgene.2016.00134 DO - 10.3389/fgene.2016.00134 ID - Meaburn2016 ER -