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Table 2 Analysis of chromosomal breaks in normal and aberrant cells of the 94P0496 cell line after irradiation

From: Evidence for a pre-malignant cell line in a skin biopsy from a patient with Nijmegen breakage syndrome

Dose 94P0496 cells Metaphases analysed Chromatid breaks Chromatid translocat. Chromos. breaks Total Breaks Breaks/ metaphase
0 Gy normal 23 5 – – 5 0.22
aberrant 42 10 – 2 12 0.29
0.5 Gy normal 20 23 – 6 29 1.45
aberrant 42 53 4 9 66 1.57
1.0 Gy normal 21 39 – 10 49 2.3
aberrant 43 125 6 13 144 3.4
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Molecular Cytogenetics

ISSN: 1755-8166