Table 1 Additional phenotypes of patients with syndromic obesity
From: Chromosomal microarray analysis in the genetic evaluation of 279 patients with syndromic obesity
Clinical features | Total cohort (n) | Patients with PCNVs (n) |
|---|---|---|
Intellectual/developmental disabilities | 219 | 55 |
Craniofacial dysmorphism | 149 | 49 |
Behavioral problems | 132 | 29 |
Hyperphagia | 112 | 27 |
Infantile hypotonia | 88 | 32 |
Language impairments | 80 | 28 |
Hands/ft abnormalities | 65 | 21 |
Abnormal external genitalia | 56 | 20 |
Eye/vision problems | 51 | 16 |
Seizures | 31 | 13 |
Poor motor skills | 29 | 9 |
Skeletal anomalies | 23 | 9 |
Brain abnormalities | 19 | 7 |
Hearing loss | 13 | 6 |
Cardiac abnormalities | 10 | 4 |