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Table 1 Probes and libraries used for FISH

From: Bone marrow failure may be caused by chromosome anomalies exerting effects on RUNX1T1 gene

Pt Chromosome Probes/libraries Band localization Genomic Localization (bp) (hg19)
1 8 AML1/ETOa
WCP 1b
designed for t(8;21)
Whole chromosome paint library
2 2 WCP 2b
CTD-2314L14c
CTD-2599D22c
ALKd
CTD-3028D11 c
CTD-2232H14c
CTD-2566H13c
CTD-2532N8c
CTD-2371H10c
CTD-2382F21c
CTD-2052G24c
CTD-3058K15c
Whole chromosome paint library
2p23.3
2p23.2
2p23.2–23.1
2p23.1
2p22.2
2p22.2–22.1
2p21.3
2p21.1
2p16.3
2p15
2p15–14
27,436,476–27,577,216 bp
29,678,603–29,819,833 bp
-
31,532,615–31,667,611 bp
36,717,490–36,828,693 bp
38,563,970–38,725,504 bp
42,157,290–42,301,116 bp
46,582,036–46,715,607 bp
48,326,711–48,434,143 bp
61,463,234–61,600,608 bp
64,034,477–64,232,972 bp
8 WCP 8b
AML1/ETOa
CTD-2341G19c
CTD-2246G22c
CTD-3245G9c
CTD-2330N9c
Whole chromosome paint library designed for t(8;21)
8q21.13
8q21.3
8q21.3
8q21.3
-
83,886,651–83,982,215 bp
87,885,140–87,980,460 bp
91,740,722–91,959,017 bp
92,778,106–92,922,619 bp
  1. aAML1/ETO translocation, dual fusion probe, Cytocell Technologies, Cambridge, UK
  2. bWCP, Cytocell Technologies, Cambridge, UK
  3. cBAC probes, Thermo Fisher Scientific, Waltham, MA, USA
  4. dZytoLight SPEC ALK Dual Color Break Apart probe, Zytovision GmbH, Bremerhaven, Germany