Skip to main content

Table 2 Univariate and multivariate Cox Regression analysis for disease recurrence considering the five PTEN deletion subtypes. Multivariate analysis exhibits age-adjusted results. PTEN intact was set as the baseline for the model. *Significant P-value < 0.05

From: Distinct subtypes of genomic PTEN deletion size influence the landscape of aneuploidy and outcome in prostate cancer

Univariate

   

Multivariate

    
 

P

HR

95% C.I.

 

P

HR

95% C.I.

   

Lower

Upper

   

Lower

Upper

Small Interstitial

0.32

0.373

0.052

2.694

Small Interstitial

0.38

0.419

0.058

3.039

Large Interstitial

0.04*

1.845

1.012

3.367

Large Interstitial

0.04*

1.844

1.007

3.377

Large Proximal

0.72

1.239

0.387

3.960

Large Proximal

0.74

1.213

0.379

3.881

Large Terminal

0.13

1.705

0.845

3.440

Large Terminal

0.19

1.587

0.785

3.208

Extensive

0.13

2.955

0.719

12.153

Extensive

0.22

2.448

0.584

10.258

PTEN Intact

0.26

.

.

.

PTEN Intact

0.38

.

.

.

Age

0.15

1.024

0.991

1.057

Age

0.18

1.022

0.990

1.055

Percentage of genome altered

0.009*

1.745

1.147

2.654

Percentage of genome altered

0.02*

1.629

1.065

2.491

  1. PTEN intact was set as a baseline in the model. Percentage of genome altered was dichotomized in high (>average) and low (≤average)