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Table 2 Univariate and multivariate Cox Regression analysis for disease recurrence considering the five PTEN deletion subtypes. Multivariate analysis exhibits age-adjusted results. PTEN intact was set as the baseline for the model. *Significant P-value < 0.05

From: Distinct subtypes of genomic PTEN deletion size influence the landscape of aneuploidy and outcome in prostate cancer

Univariate     Multivariate     
  P HR 95% C.I.   P HR 95% C.I.
    Lower Upper     Lower Upper
Small Interstitial 0.32 0.373 0.052 2.694 Small Interstitial 0.38 0.419 0.058 3.039
Large Interstitial 0.04* 1.845 1.012 3.367 Large Interstitial 0.04* 1.844 1.007 3.377
Large Proximal 0.72 1.239 0.387 3.960 Large Proximal 0.74 1.213 0.379 3.881
Large Terminal 0.13 1.705 0.845 3.440 Large Terminal 0.19 1.587 0.785 3.208
Extensive 0.13 2.955 0.719 12.153 Extensive 0.22 2.448 0.584 10.258
PTEN Intact 0.26 . . . PTEN Intact 0.38 . . .
Age 0.15 1.024 0.991 1.057 Age 0.18 1.022 0.990 1.055
Percentage of genome altered 0.009* 1.745 1.147 2.654 Percentage of genome altered 0.02* 1.629 1.065 2.491
  1. PTEN intact was set as a baseline in the model. Percentage of genome altered was dichotomized in high (>average) and low (≤average)