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Fig. 4 | Molecular Cytogenetics

Fig. 4

From: Distinct subtypes of genomic PTEN deletion size influence the landscape of aneuploidy and outcome in prostate cancer

Fig. 4

Enrichment analysis of gene expression in deletion subtypes with extensive aneuploidy. Two PTEN deletion subtypes had distinctive patterns of aneuploidy and were significantly enriched for pathways related to cancer progression. The Large Interstitial subtype (a) was enriched for metabolism, cell structural adhesion and also angiogenesis. The Large Proximal deletions (b) showed effects in pathways associated with cell metabolism and structure. Enrichment analysis was performed through DAVID database and nodes were generated through Enrichment Map (Cytoscape)

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