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Table 3 Summary of the STR results for the captured fetal cells (fnRBC and/or EVT) from the 5 pregnant women. For each case, at least 4 informative STR loci are feasible to distinguish the fetal cells from the maternal cells (the non-maternal alleles are marked in bold)

From: Noninvasive prenatal diagnosis of fetal aneuploidy by circulating fetal nucleated red blood cells and extravillous trophoblasts using silicon-based nanostructured microfluidics

Locus Case 1 (Trisomy 13) Case 2 (Trisomy 18) Case 3 (Trisomy 21) Case 4 (Disomy: 46,XY) Case 5 (Disomy: 46,XX)
Maternal leukocyte fnRBC Maternal leukocyte fnRBC EVT Abortus tissue Maternal leukocyte fnRBC EVT Maternal leukocyte fnRBC Maternal leukocyte fnRBC
D3S1358 133, 137 129, 137 129, 137 129, 137 129, 137 129, 137 129, 137 129, 137 129, 137 129, 133 133, 137 129, 133 129, 133
TH01 171, 179 171, 183 167, 171 167, 179 167, 179 167, 179 171, 179 171, 179 171, 179 179 179 179 167, 179
D13S317 182, 190 182, 198 197 181, 197 181, 197 181, 197 181, 197 181, 197 181, 197 182, 194 186, 194 182, 186 182, 186
D8S1179 222, 234 218, 222 238 218, 238 218, 238 218, 238 230, 234 230 230 218, 230 218, 230 231, 239 231
D7S820 234, 238 230, 238 234 234, 238 234, 238 234, 238 226, 238 226, 238 226, 238 242, 246 234, 242 231, 243 231, 235
TPOX 272, 276 272 272 272, 284 272, 284 272, 284 272 272, 276 272, 276 272, 284 272 272, 284 284
D16S539 285 285 285, 297 289, 297 289, 297 289, 297 284 284 284 289, 297 293, 297 285, 301 297, 301
D18S51 307, 311 311 303, 315 303, 315 303, 315 303, 315 307, 319 307, 315 307, 315 307 307 315, 337 303, 315
CSF1PO 315 315, 320 344 340, 344 340, 344 340, 344 336, 344 336, 344 336, 344 344 332, 344 341 341, 349
Penta D 404, 419 404, 419 405, 414 405, 414 405, 414 405, 414 400, 424 424, 433 424, 433 419, 433 419, 433 404, 414 404, 433
Penta E 418, 451 418 429 424, 429 424, 429 424, 429 414, 419 419, 450 419, 450 445, 450 424, 450 414, 435 435, 451
AMEL 105 105 105 105 105 105 105 105 105 105 105, 111 105 105