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Fig. 1 | Molecular Cytogenetics

Fig. 1

From: Noninvasive prenatal diagnosis of fetal aneuploidy by circulating fetal nucleated red blood cells and extravillous trophoblasts using silicon-based nanostructured microfluidics

Fig. 1

a Flowchart of the PicoBioChip manufacture: 1. standard cleaning, 2. photolithography, 3. Ag deposition, 4. etching, 5. Ag and photoresist removal, and 6.surface modification. b The porous morphology on the PicoBioChip with a “nano-on-nano” structure. c Conceptual illustration of how an PicoBioChip can be employed to achieve significantly enhanced capture of targeted cell

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