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Fig. 2 | Molecular Cytogenetics

Fig. 2

From: Combination of t(4;14), del(17p13), del(1p32) and 1q21 gain FISH probes identifies clonal heterogeneity and enhances the detection of adverse cytogenetic profiles in 233 newly diagnosed multiple myeloma

Fig. 2

Distribution of abnormalities according to the number of clones at diagnosis (n = 184). 1q21 gain was more frequent in the subgroup of 2 clones or more (81.6%) compared to the subgroup of 1 clone (18.4%) (p < 0.0001), del(1p32) was more frequent in the subgroup of 3 clones or more (28.0%) compared to the subgroup of 1 or 2 clones (5.8%) (p = 0.002). No preferential distribution was observed with del(17p13) and t(4;14) translocation

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Molecular Cytogenetics

ISSN: 1755-8166