Table 2 Cytogenetic profile in comparison with national and international studies
Variables | Present study | Pakistan 1 | Pakistan 2 | Pakistan 3 | China 6 | Korea 7 | India 8 | Turkey 9 | Greece 10 | Taiwan 11 | Singapore 12 | Spain 13 | Germany 14 | Poland 15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytogenetics available/Total No. of patients | 98/177 | – | – | 71/71 | 367/508 | – | 40/40 | 54/54 | 591/855 | 175/189 | 40/43 | 640/640 | – | 276/863 |
Normal Karyotype % | 55 | – | – | 57.7 | 62.9 | – | 53 | 85 | 61.6 | 53.1 | 52.5 | 49 | – | 44.6 |
Abnormal Karyotype % | 44 | – | – | 42.3 | 37.1 | – | 47 | 15 | 38.4 | 46.8 | 47.5 | 51 | – | 55.4 |
Complex Karyotype % | 12 | – | – | 15.5 | 38.9 | – | – | – | 7.6 | 17.2 | 20 | 14 | – | 6.4 |
Monosomy 7% | 7.1 | – | – | – | – | – | 32 | – | – | |||||
Del(5q) % | 6.1 | – | – | 2.8 | 12.5 | – | 6 | 2.7 | 9.1 | 15 | 5 | – | 19 | |
Del(7q) % | 2 | – | – | 4.2 | 4.4 | – | 3 | 14.9 | 7.5 | 4 | – | 1.8 | ||
Trisomy 8% | 3 | – | – | 9.9 | 25.7 | – | 16 | 9 | 8.3 | 12 | 10 | 5 | – | 2.2 |
Del(20q) % | 4 | – | – | 1.4 | 14.7 | – | 2.2 | 6.3 | 1 | – | 0.3 | |||
Trisomy 21% | 1 | – | – | – | – | – | – | – | – | – | – | – | – | – |
t(1;9) (q11;q34) along with Del(9q)a % | 1 | – | – | – | – | – | – | – | – | – | – | – | – | – |
Trisomy 8 with Del(7q)b % | 1 | – | – | – | – | – | – | – | – | – | – | – | – | – |
t(6:9) (p23;q23)b % | 1 | – | – | – | – | – | – | – | – | – | – | – | – | – |
Monosomy 7,8b % | 1 | – | – | – | – | – | – | – | – | – | – | – | – | – |
Del(9q)b % | 2 | – | – | – | – | – | – | – | – | – | – | – | – | – |