Table 1 Copy number aberrations associated with DDLPS subtype
From: Application of high-resolution genomic profiling in the differential diagnosis of liposarcoma
Copy number aberration | WDLPS n (%) | DDLPS n (%) | P value (2-tailed Fisher’s exact test) |
|---|---|---|---|
Losses of chromosome 6 | 0 | 9 (39) | 0.002 |
6p23p22.2 6q11.1q12 6q15q22.33 | 0 0 0 | 6 (26) 3 (13) 3 (13) | 0.022 0.233 0.233 |
Losses of chromosome 11 a | 0 | 6 (26) | 0.022 |
11p15.5p13 11q23.2q24.2 | 0 0 | 3 (13) 4 (17) | 0.233 0.109 |
Losses of chromosome 13q a | 0 | 7 (30) | 0.009 |
13q11q31.1 | 0 | 7 (30) | 0.009 |
Gains of chromosome 14q | 3 (13) | 10 (43) | 0.047 OR = 0.2 95% Cl [0.05–0.85] |
14q21.2q21.3 | 2 (9) | 9 (39) | 0.035 |
OR = 0.2 95% Cl [0.03–0.79] | |||
14q32.2q32.31 | 2 (9) | 2 (9) | 1 |